In 2013 diabetes and pre-diabetes in Mauritius had a prevalence of 50% in the population aged 23 to 74. The development of a low glycemic index (GI) sugar could help to control diabetes not only in Mauritius but worldwide. Thus a project was undertaken with the objective to co-crystalize a food grade, low GI material into refined sugar crystal, with the goal to lower its GI. Polyols are well known food grade materials used commercially in nutrition and medicine; many have very low GI’s, a sweet taste and can be prepared from cane sugar. A bench scale pilot crystallizer unit was constructed and tested. The equipment was used to develop a process for co-crystallization of sucrose with polyols and sucrose-polyol co-crystals containing up to 30% of the polyol were successfully produced. The resulting co-crystallized product had definite functional benefits such as lower calorific value and lower glycemic load.