Interplay between dietary sugars and fats and insulin resistance
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Date Uploaded:
29 August 2022
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Diet composition has been speculated to play a marked role on insulin resistance and hence on increasing the risk to the development of several chronic diseases including cardiovascular disease, diabetes, and Alzheimer’s disease. Cardiovascular diseases and diabetes are among the top leading causes of death worldwide, and there is a dire need to understand the exact roles of the dietary components. Dietary fats and sugars have been linked to insulin resistance via several mechanisms primarily via inflammation and oxidative stress. This chapter thus highlights the mechanisms of action through which dietary sugars and fats (saturated and unsaturated) culminate to insulin resistance. Evidences regarding the nonconclusive findings to link high dietary sugars and fats to insulin resistance in clinical trials are also discussed.